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Western blot analysis of extracts of various cell lines, using VASP Rabbit mAb (A8862) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
VASP Rabbit mAb
Catalog No：AB-A8862
Manufacturer：ABclonal
Synonyms：VASP; vasodilator-stimulated phosphoprotein
Applications：WB
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€125,00 – €485,00
| Product Name: | VASP Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008] |
| Immunogen: | A synthesized peptide derived from human VASP |
| Gene ID: | 7408 |
| Swiss prot: | P50552 |
| Molecular weight: | 46kDa |
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