OTUD5 Rabbit pAb
Catalog No：AB-A20516
Manufacturer：ABclonal
Synonyms：DUBA; MCAND
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€110,00 – €325,00
| Product Name: | OTUD5 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 362-571 of human OTUD5 (NP_060072.1). |
| Gene ID: | 55593 |
| Swiss prot: | Q96G74 |
| Molecular weight: | 60kDa |
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