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Western blot analysis of extracts of various cell lines, using MYO6 antibody (A13033) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
MYO6 Rabbit pAb
Catalog No：AB-A13033
Manufacturer：ABclonal
Synonyms：MYO6;DFNA22;DFNB37;Myo6-007;Myo6-008;myosin VI
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€100,00 – €370,00
| Product Name: | MYO6 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1285 of human MYO6 (NP_004990.3). |
| Gene ID: | 4646 |
| Swiss prot: | Q9UM54 |
| Molecular weight: | 145kDa/146kDa/148kDa/149kDa |
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