MLLT11 Rabbit pAb
Catalog No：AB-A20410
Manufacturer：ABclonal
Synonyms：AF1Q
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€110,00 – €325,00
| Product Name: | MLLT11 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human MLLT11 (NP_006809.1). |
| Gene ID: | 10962 |
| Swiss prot: | Q13015 |
| Molecular weight: | 10kDa |
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