Western blot analysis of extracts of various cell lines, using IYD antibody (A9206) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
IYD Rabbit pAb
Catalog No:AB-A9206
Manufacturer:ABclonal
Synonyms:IYD;C6orf71;DEHAL1;IYD-1;TDH4
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€100,00 – €370,00
Product Name: | IYD Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-214 of human IYD (NP_981932.1). |
Gene ID: | 389434 |
Swiss prot: | Q6PHW0 |
Molecular weight: | 22kDa/28kDa/31kDa/32kDa/33kDa |
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