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Western blot analysis of extracts of various cell lines, using GAB2 antibody (A13066) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit (RM00021).|Exposure time: 90s.
GAB2 Rabbit pAb
Catalog No：AB-A13066
Manufacturer：ABclonal
Synonyms：GAB2
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€100,00 – €370,00
| Product Name: | GAB2 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 377-676 of human GAB2 (NP_536739.1). |
| Gene ID: | 9846 |
| Swiss prot: | Q9UQC2 |
| Molecular weight: | 69kDa/74kDa |
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