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Western blot analysis of extracts of A-549 cells, using FBXW5 antibody (A9345) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
FBXW5 Rabbit pAb
Catalog No：AB-A9345
Manufacturer：ABclonal
Synonyms：FBXW5;Fbw5
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€100,00 – €370,00
| Product Name: | FBXW5 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 184-566 of human FBXW5 (NP_061871.1). |
| Gene ID: | 54461 |
| Swiss prot: | Q969U6 |
| Molecular weight: | 42kDa/63kDa |
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