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Western blot analysis of extracts of various cell lines, using EWSR1 Rabbit mAb (A9640) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
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Immunohistochemistry of paraffin-embedded rat lung using EWSR1 Rabbit mAb (A9640) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human appendix using EWSR1 Rabbit mAb (A9640) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse testis using EWSR1 Rabbit mAb (A9640) at dilution of 1:100 (40x lens).
EWSR1 Rabbit mAb
Catalog No：AB-A9640
Manufacturer：ABclonal
Synonyms：EWS, EWS-FLI1, bK984G1.4
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
| Product Name: | EWSR1 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009] |
| Immunogen: | A synthesized peptide derived from human EWSR1 |
| Gene ID: | 2130 |
| Swiss prot: | Q01844 |
| Molecular weight: | 85kDa |
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