CEP78 Rabbit pAb
Catalog No:AB-A20405
Manufacturer:ABclonal
Synonyms:IP63; CRDHL; C9orf81
Applications:WB
Reactivity:Human
Host:Rabbit
Conjugate:No
€125,00 – €370,00
Product Name: | CEP78 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a centrosomal protein that is both required for the regulation of centrosome-related events during the cell cycle, and required for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive LRR repeats, and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 to the distal end of the centriole. Naturally occurring mutations in this gene cause defects in primary cilia that result in retinal degeneration and sensorineural hearing loss which are associated with cone-rod degeneration disease as well as Usher syndrome. Low expression of this gene is associated with poor prognosis of colorectal cancer patients. |
Immunogen: | Recombinant protein of human CEP78. |
Gene ID: | 84131 |
Swiss prot: | |
Molecular weight: |
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