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Western blot analysis of extracts of various cell lines, using Ataxin 3 antibody (A12992) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
Ataxin 3 Rabbit pAb
Catalog No：AB-A12992
Manufacturer：ABclonal
Synonyms：ATXN3;AT3;ATX3;JOS;MJD;MJD1;SCA3;ataxin-3;Ataxin 3
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€100,00 – €370,00
| Product Name: | Ataxin 3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human Ataxin 3 (NP_004984.2). |
| Gene ID: | 4287 |
| Swiss prot: | P54252 |
| Molecular weight: | 20kDa/35kDa/39kDa/41kDa |
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