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Western blot analysis of extracts of various cell lines, using ACTN2 Rabbit mAb (A8939) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
ACTN2 Rabbit mAb
Catalog No：AB-A8939
Manufacturer：ABclonal
Synonyms：CMD1AA, CMH23
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€125,00 – €485,00
| Product Name: | ACTN2 Rabbit mAb |
| Category: | Monoclonal Antibodies |
| Description: | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] |
| Immunogen: | A synthesized peptide derived from human ACTN2 |
| Gene ID: | 88 |
| Swiss prot: | P35609 |
| Molecular weight: | 103kDa |
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